Original scientific paper
Prediction of the Y-Chromosome Haplogroups within a recently settled Turkish Population in Sarajevo, Bosnia & Herzegovina
Serkan Doğan
orcid.org/0000-0001-6932-7165
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Gülşen Doğan
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Adna Ašić
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Larisa Bešić
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Biljana Klimenta
; Dom Zdravlja, Sarajevo, Bosnia and Herzegovina
Mirsada Hukić
; Department of Medical Science, Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina
Yusuf Turan
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Dragan Primorac
; University of Split, School of Medicine and Department of Forensic Science, Split, Croatia
Damir Marjanović
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Abstract
Analysis of Y-chromosome haplogroup distribution is widely used when investigating geographical clustering of different populations, which is why it plays an important role in population genetics, human migration patterns and even in forensic investigations. Individual determination of these haplogroups is mostly based on the analysis of single nucleotide polymorphism (SNP) markers located in the non-recombining part of Y-chromosome (NRY). On the other hand, the number of forensic and anthropology studies investigating short tandem repeats on the Y-chromosome (Y-STRs) increases rapidly every year. During the last few years, these markers have been successfully used as haplogroup prediction methods, which is why they have been used in this study. Previously obtained Y-STR haplotypes (23 loci) from 100 unrelated Turkish males recently settled in Sarajevo were used for the determination of haplogroups via ‘Whit Athey’s Haplogroup Predictor’ software. The Bayesian probability of 90 of the studied haplotypes is greater than 92.2% and ranges from 51.4% to 84.3% for the remaining 10 haplotypes. A distribution of 17 different haplogroups was found, with the Y-haplogroup J2a being most prevalent, having been found in 26% of all the samples, whereas R1b, G2a and R1a were less prevalent, covering a range of 10% to 15% of all the samples. Together, these four haplogroups account for 63% of all Y-chromosomes. Eleven haplogroups (E1b1b, G1, I1, I2a, I2b, J1, J2b, L, Q, R2, and T) range from 2% to 5%, while E1b1a and N are found in 1% of all samples. Obtained results indicate that a large majority of the Turkish paternal line belongs to West Asia, Europe Caucasus, Western Europe, Northeast Europe, Middle East, Russia, Anatolia, and Black Sea Y-chromosome lineages. As the distribution of Y-chromosome haplogroups is consistent with the previously published data for the Turkish population residing in Turkey, it was concluded that the analyzed population could also be recognized as a representative sample of the Turkish population residing in Turkey.
Keywords
Y-STR; Y-SNP; Y chromosome; haplotypes; haplogroup predictor; Turkish population
Hrčak ID:
166650
URI
Publication date:
18.1.2016.
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