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Original scientific paper

The rise and fall of resistant bacteria

Arjana Tambić Andrašević ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Marija Gužvinec ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Anja Bukovac ; Geonatura d.o.o., Zagreb, Hrvatska
Sandra Lucić ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska
Silvija Šoprek ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska


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Abstract

Antimicrobial resistance (AMR) is one of the leading problems in modern medicine. Antibiotic resistance surveillance in Croatia was set up in 1996 and antibiotic resistance rates in most frequent bacterial pathogens were analysed for the period 2000 till 2014. Thirty five Croatian microbiology laboratories (population coverage >90 %) have sent antibiotic sensitivity data for clinical isolates (copy isolates were excluded) to the Ministry of Health Reference Center for Antibiotic Resistance Surveillance where these data were aggregated and analysed. Macrolide resistance in group Astreptococci shows a mild decreasing trend. Penicillin non-susceptibility in pneumococci demonstrates slight oscillations without any trend. Vancomycin resistance was recorded in Enterococcus faecium with increasing trend in the last two years. Resistance to 3rd generation cephalosporins and quinolones is slightly but constantly increasing in E. coli and in K. pneumoniae, although significantly higher, it does not demonstrate increase in the last few years. Carbapenem resistance is slightly increasing in P. aeruginosa and has abruptly increased in A. baumannii since 2008. Croatia has a well organized antibiotic resistance surveillance network and knowing local resistance rates is an important first step in controlling antibiotic resistance. For successful AMR control it is also very important to strengthen the role of infection control teams and to establish antibiotic stewardship teams.

Keywords

Antibiotics; resistance; surveillance

Hrčak ID:

166678

URI

https://hrcak.srce.hr/166678

Publication date:

31.12.2015.

Article data in other languages: croatian

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