Original scientific paper

https://doi.org/10.21860/medflum2016_4coa

Allergic sensitization related to age and clinical presentation

Tea Crnogaj ; Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Bojana Đokić ; Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Milana Đorđevski ; Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Monika Mačkić ; Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Barbara Kvenić ; Klinika za pedijatriju, KBC Rijeka, Rijeka
Srđan Banac orcid.org/0000-0002-2855-4609 ; Klinika za pedijatriju, KBC Rijeka, Rijeka

Abstract

Aim: To determine sensitization profile and allergic triggers related to allergic disease and the age of the child. Subjects and methods: Results of skin prick tests were retrospectively analyzed to inhalational and nutritive allergens in the local population of subjects (n=1102; age 0-18 years; 58% (n=640) boys and 42% (n=462) girls) who suffer from asthma associated with allergic rhinitis or rhinoconjunctivitis 29% (n=323), allergic rhinitis 24% (n=269), atopic eczema 21% (n=226), allergic rhinoconjunctivitis 13% (n=148), allergic asthma 8% (n=85) and acute allergic urticaria 5% (n=51). Data considering diretcly notable triggers of allergic symptoms were obtained from medical history. Results: Sensitization to nutritive allergens dominates in infants (P=0.001). Sensitization to inhalant allergens has siginificant frequency in children after three years of age Sensitization to mite allergens and hairy pets appeared firstly (P=0.003). Sensitization to pollen becomes significant at school age. In subjects with asthma and allergic rhinitis dominate sensitization to inhalant allergens, mostly on mites (P=0.007), except in allergic rhinoconjunctivitis where sensitization to grass pollen is dominant. Subjects with eczema and acute urticaria are mostly sensitized to nutritive allergens such as eggs, nuts and cow's milk. However, sensitization to mites seems to be also important. Allergens are seldom observed as direct triggers of allergic symptoms. In case they are mostly associated with pollination, with hairy pets and with the consumption of eggs. Conclusion: The results are of practical importance for everyday evaluation of allergic sensitization in local population of patients. They can help in the rational selection of current and relevant allergens for skin prick testing taking care of the child's age and its allergic disease or symptoms.

Keywords

allergen; child; skin test

Hrčak ID:

168451

URI

https://hrcak.srce.hr/168451

Publication date:

1.12.2016.

Article data in other languages: croatian

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