Original scientific paper
Amino acid changes in rat testis in manganese poisoning
P.P. Kar
; lndustrial Toxicology Research Centre, Chattar Manzil Palace, Lucknow, U. P., India
S.J. Mustafa
; lndustrial Toxicology Research Centre, Chattar Manzil Palace, Lucknow, U. P., India
V. Chandra Satya
; lndustrial Toxicology Research Centre, Chattar Manzil Palace, Lucknow, U. P., India
Abstract
Rats were given manganese chloride (8 mg/kg) intraperitoneally daily. Manganese content and various amino acids were estimated in the testis at 30 and 60 days. In this period manganese content of the testis showed a 4- and 9-fold increase respectively. Amino acids remained unaltered al 30 days while at 60 days, the amounts of alanine, cysteine, leucine, proline, phenylalanine and glutamine were significantly greater than the levels in the control animals. The present experiments show a great affinity of testicular tissue for manganese resulting in biochemical alterations.
Keywords
Hrčak ID:
168619
URI
Publication date:
22.3.1973.
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