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The Application of Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: Which Applications are Evidence Based?

Anton Sculean
Adrian Kašaj
Britta Willershausen

Full text: croatian pdf 90 Kb

page 215-222

downloads: 639


Full text: english pdf 78 Kb

page 223-228

downloads: 613



The goal of regenerative periodontal therapy is the reconstitution of the lost periodontal structures (i.e. the new formation of root cementum, periodontal ligament and alveolar bone). Results from basic research have pointed to the important role of the enamel matrix protein derivative (EMD) in periodontal wound healing. Histological results of experiments in animals and of human case reports have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. The goal of the current overview is to present, based on the existing evidence, the clinical indications for regenerative therapy with EMD.


enamel matrix protein derivative, cementogenesis, surgical periodontal therapy, periodontal regeneration

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