Original scientific paper

https://doi.org/10.15836/ccar2016.598

Achieving Blood Pressure Control with Telmisartan and Fixed Dose Combination of Telmisartan and Hydrochlorothiazide.

Ana Zaletel ; Krka, d. d., Novo mesto, Slovenia
Polona Knavs Vrhunec ; Krka, d. d., Novo mesto, Slovenia
Breda Barbič-Žagar orcid.org/0000-0002-1173-7361 ; Krka, d. d., Novo mesto, Slovenia

Abstract

Arterial hypertension represents the main cause of cardiovascular disorders, such as myocardial infarction, ischemic stroke, heart failure, renal insufficiency, and other clinical events. Therefore, an effective antihypertensive pharmacotherapy is clearly needed, in addition to proper lifestyle changes, in order to provide not only symptomatic relief but also cardiovascular protection. The TANDEM study was undertaken to evaluate the efficacy and safety of telmisartan monotherapy (Tolura®) and the fixed-dose combination of telmisartan/hydrochlorothiazide (Tolucombi®) in adult hypertensive patients. A total of 1,234 patients were enrolled in this non-interventional post-authorization efficacy and safety study. Patients were treated with telmisartan monotherapy or the fixed-dose combination of telmisartan/hydrochlorothiazide once daily for four months. The study demonstrated that Tolura® and Tolucombi® reduce systolic and diastolic blood pressure significantly (p<0.0001) and that they are well tolerated by hypertensive patients.

Keywords

hypertension; blood pressure; efficacy; safety; telmisartan

Hrčak ID:

170033

URI

https://hrcak.srce.hr/170033

Publication date:

31.10.2016.

Article data in other languages: croatian

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