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Review article

PLACEBO IN THE PAIN TREATMENT

Slavica Kvolik
Marko Jukić
Mira Fingler


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Abstract

Use of medical preparations having no specific pharmacological activity or dummy procedures administered to patients is known as placebo. Such maneuvers are important in the pain treatment and clinical studies investigating pain mechanisms. Several recent studies have shown that placebo treatment produces measurable psychophysiological effects, characterized by changes in specific brain functions and decreased subjective pain perception. This article reviews changes observed in placebo analgesia, its intensity as compared to active compounds, and principal problems observed during the placebo treatment and in clinical trials.

Keywords

Pain – drug therapy, psychology; Analgesics – therapeutic use; Placebos – therapeutic use, pharmacology; Placebo effect; Brain – drug effects; Pain measurement – drug effects; Ethics, clinical

Hrčak ID:

172438

URI

https://hrcak.srce.hr/172438

Publication date:

27.8.2012.

Article data in other languages: croatian

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