Liječnički vjesnik, Vol. 135 No. 11-12, 2013.
Review article
ACUTE-ON-CHRONIC LIVER FAILURE (ACLF) – A NEW ENTITY IN HEPATOLOGY?
Ivana Mikolašević
Mladen Radić
Sandra Milić
Davor Štimac
Abstract
Recently, acute-on-chronic liver failure has been recognized as a specific and unique clinical form of liver failure (usually related to acute insult) in patients with previously known or unknown compensated chronic liver disease. Its main feature is the reversibility, and high short-mortality due to multiorgan failure (MOF) in the absence of liver support system devices and/or liver transplantation. This article aims to introduce the definition and better understanding of this newly developed and unique profile of liver failure.
Keywords
Liver failure, acute – classification, etiology, physiopathology, therapy, mortality; End stage liver disease – classification, etiology, physiopathology, therapy, mortality; Multiple organ failure – etiology, mortality
Hrčak ID:
172527
URI
Publication date:
30.12.2013.
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