Liječnički vjesnik, Vol. 137 No. 3-4, 2015.
Professional paper
FIRST SYNCHRONOUS LIVER RESECTION AS A PART OF CYTOREDUCTIVE SURGERY, PERITONECTOMY AND HIPEC IN CROATIA – CASE REPORT
Ana Majsec Budak
Mate Škegro
Mate Majerović
Dubravko Smuđ
Željko Jelinčić
Emil Kinda
Tihomir Kekez
Goran Augustin
Hrvoje Silovski
Petar Matošević
Tomislav Bruketa
Abstract
We present a case of a 37-year-old female, with large adenocarcinoma of transverse colon, and metastases in spleen, liver, peritoneum, greater omentum, gall bladder and right adnexa. She was transferred to our Hospital, and extensive elective cytoreductive surgery with intraabdominal hyperthermal chemotherapy (HIPEC) was performed. Couple of months later, she was operated on for a newly evidenced secondary nodus in liver segment VII, and metastasectomy was performed. Throughout entire postoperative period she was receiving cyclic chemotherapy. At this point, 2 years from the first operation, she was without evidenced recurrence of the disease. Aggressive cytoreductive surgery with multiorgan resection, peritonectomy, HIPEC and adjuvant chemotherapy which was proved to be a feasible option in some patients, with synchronous liver resection (LR) proved to be feasible and beneficial for patients with three or fewer liver metastases. This is the first liver resection included in usually performed cytoreductive surgery and HIPEC in Croatia.
Keywords
Adenocarcinoma – drug therapy, surgery, pathology, secondary; Colonic neoplasms – pathology, drug therapy, surgery; Colon, transverse – surgery; Peritoneal neoplasms – drug therapy, surgery, secondary; Peritoneum – surgery; Liver neoplasms – drug therapy, surgery, secondary; Hepatectomy; Antineoplastic combined chemotherapy protocols – therapeutic use; Chemotherapy, cancer, regional perfusion; Hyperthermia, induced; Combined modality therapy; Survival analysis
Hrčak ID:
172688
URI
Publication date:
5.5.2015.
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