Professional paper
Postmarketing research of the efficacy and tolerability of fluconazole and clotrimazole in the treatment of vulvovaginal Candidiasis
V. Škerk
J. Jakšić
T. Žarković
D. Škalko
J. Begovac
Abstract
Atotal of 246 episodes of uncomplicated vulvovaginal candidiasis (VVC) were examined at gynecological outpatient primary health care departments in the period from June 1, 2006 until July 31, 2006, in patients aged 18 to 45 years in whom the symptoms lasted up to two weeks before treatment. The occurrence of VVC in 83 patients was preceded by antibiotic consumption, menstruation or taking oral contraceptives. Other patients had no predisposing factors. Sexual partners did not experience balanitis. The patients were treated according to the randomization list with either clotrimazole 1×0,2 g vaginally for 3 days or a single dose of fluconazole 1×150 mg perorally. The randomization also determined patients whose sexual partners received a single dose of fluconazole 1×150 mg perorally.
Clinical efficacy of antimicrobial treatment of uncomplicated VVC and the frequency of recurring episodes of VVC did not significantly differ with regards to the type of administered treatment or simultaneous treatment or no treatment of sexual partner.
Keywords
Fluconazole; clotrimazole; vulvovaginal candidiasis
Hrčak ID:
12690
URI
Publication date:
14.9.2006.
Visits: 1.811 *