Review article
https://doi.org/10.21860/medflum2017_173386
Probiotic use in the prevention and therapy of atopic dermatitis
Mia Prebeg
; Dom zdravlja Primorsko-goranske županije, Rijeka
Ines Brajac
; KBC Rijeka, Klinika za dermatovenerologiju, Rijeka
Abstract
The prevalence of atopic dermatitis (AD) has risen over the past decades, and this is especially expressed in western countries. Reduced microbial exposure during infancy and therefore reduced stimulation of immune system is considered to be the cause for this rising prevalence. Intestinal microbiota represents the first and major source of microbial exposure and therefore the changes in its composition and diversity are considered to be responsible for development of AD. That is why probiotics are, owing to their ability to manipulate the composition of microbiota and their immunomodulatory effects, considered to be a promising prevention and therapeutic intervention of atopic dermatitis. Former studies indicate that they have a preventing potential, but their therapeutic effects have not been proven. However, probiotic use in AD is a subject of reasearches at the moment, and future studies should clearify if they deserve a place among the other preventive and therapeutical measures and resolve uncertanities regarding their administration.
Keywords
atopic dermatitis; prevention; probiotics; therapy
Hrčak ID:
173386
URI
Publication date:
1.3.2017.
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