Professional paper
Characteristics and empiric antimicrobial therapy of urinary tract infections in patients treated at the Departement of Infectious Diseases, General Hospital »Dr. Josip Benčević« in Slavonski Brod
N. Pandak
J. Fornet-Šapčevski
B. Križanović
M. Šiško
T. Stojadinović
Abstract
Urinarv tract infections (UTI) are one of the most common reasons for seeking medical consultation and therefore are among the most frequent reasons for antibiotic prescription. The purpose of this paper is the analvsis of the most common etiologic agents of UTI in our environment, registration of the degree of bacterial resistance, and evaluation of empiric antibiotic therapv success. Retrospectively data of patients, hospitalized during year 2004, at the Departement of Infectious Diseases, General Hospital »Dr. Josip Benčević« in Slavonski Brod, due to acute urinarv tract infections, were analysed. The most common cause of UTI was Escherichia coli, although in male patients with complicated UTI, the most common cause was Pseudomonas aeruginosa. Since 45% of Escherichia coli were amoxicillin resistant, and 35% trimethoprim-sulfamethoxazole resistant, these antimicrobials can't be used as empiric therapy drugs in our environment. As much as 65% of Pseudomonas aeruginosa were gentamicin and 45% ciprofloxacin resistant. The most frequent empiric antibiotic therapy failure was observed in male patients with complicated UTI, so the best empiric drug choice for these patients, in our situation, would be piperacillin/tazobactam, carbapenems or cefepime.
Keywords
Urinary tract infections; etiology; empiric antimicrobial therapy
Hrčak ID:
12698
URI
Publication date:
5.5.2006.
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