Original scientific paper

THE METABOLIC SYNDROME IS ASSOCIATED WITH SELF-REPORTED PHYSICAL COMPLAINTS IN PATIENTS WITH BIPOLAR DISORDER

Davy Vancampfort ; KU Leuven – University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium; KU Leuven – University of Leuven, University Psychiatric Center KU Leuven, Campus Kortenberg, Belgium
Pascal Sienaert ; KU Leuven – University of Leuven, University Psychiatric Center KU Leuven, Campus Kortenberg, Belgium
Sabine Wyckaert ; KU Leuven – University of Leuven, University Psychiatric Center KU Leuven, Campus Kortenberg, Belgium
Marc De Hert ; KU Leuven – University of Leuven, University Psychiatric Center KU Leuven, Campus Kortenberg, Belgium
Brendon Stubbs ; Physiotherapy Department, South London and Maudsley NHS Foundation Trust, London, UK; Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK
Eugene Kinyanda ; Department of Psychiatry, Makerere University College of Health Sciences, School of Health Sciences, Kampala, Uganda; MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda
Michel Probst ; KU Leuven – University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium

Abstract

Background: The prevalence of metabolic syndrome (MetS) in patients with bipolar disorder is 35 to 40%. It is, however, not
established yet whether MetS influences participation in physical activity, walking capacity and global functioning.
Subjects and methods: Sixty-five patients (36 ♀) received a full-fasting laboratory screening, performed a walk test including
self-report of pre- and post-test pain, and completed the International Physical Activity Questionnaire and the Quick Inventory of
Depressive Symptomatology Self Report (QIDS-SR16).
Results: Patients with (n=24) and without (n=41) MetS did not significantly differ in age, gender, psychotropic medication
doses, physical activity, smoking behaviour and global functioning. In contrast, patients with MetS had a significantly (a) longer
illness duration, (b) higher BMI, and (c) lower walking capacity. Moreover, patients with MetS scored significantly higher on the
QIDS. Patients with MetS reported more pain before and after the walking test and more dyspnea following 6 minutes of walking,
indicating the physical health challenges facing people with bipolar disorder and MetS seeking to engage in physical activity.
Conclusion: The current data give further credence to the importance of interventions promoting the walking capacity in people
with bipolar disorder, in particular in these patients at a high risk for cardiovascular diseases.

Keywords

metabolic syndrome; bipolar disorder; physical activity; exercise; physical fitness

Hrčak ID:

175260

URI

https://hrcak.srce.hr/175260

Publication date:

7.6.2016.

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