Croatica Chemica Acta, Vol. 62 No. 2B, 1989.
Original scientific paper
Circular Dichroism and Absorption Spectra of Monoand Di-Aminoacridines Complexed to DNA
Daniel Fornasiero
; Department of PhysicaL and Inorganic Chemistry, University of Adelaide, Adelaide 5001, South Australia
Tomas Kurucsev
; Department of PhysicaL and Inorganic Chemistry, University of Adelaide, Adelaide 5001, South Australia
Reidar Lyng
; Department of Physical Chemistry, Chalmers University of Technology, S-412 96 Gothenburg, Sweden
Bengt Norden
; Department of Physical Chemistry, Chalmers University of Technology, S-412 96 Gothenburg, Sweden
Abstract
The absorption and circular dichroism spectra of the intercalation
complexes with DNA of the 9-aminoacridine chromophore
in mono- and bisfunctional forms have been determined in the
visible/near-ultraviolet region. The experimental spectra were
deconvoluted into contributions from three (It*, n) transitions and
the dipole and rotatory strengths of one long-axis and one shortaxis
polarized transition were determined for each intercalating
species. The experimental results were compared with theoretical
calculations of the induced CD of intercalation complexes and a
series. of inferences were drawn concerning the geometry of the
complexes.
Keywords
Hrčak ID:
175500
URI
Publication date:
10.8.1989.
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