Croatica Chemica Acta, Vol. 58 No. 4, 1985.
Review article
Nonactin and the Coupe du Roi
Kurt Mislow
; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, U.S.A.
Abstract
The macrolide antibiotic nonactin is the first example of a natural product with S4 symmetry. It is now pointed out that the synthesis of nonactin by dimerization-cyclization of (-)-nonactyl- (+ )-nonactic acid, reported by Ulrich Schmidt in 1975, is also the first example of a chemical combination of two homochiral molecules to give an achiral product.
Keywords
Hrčak ID:
178018
URI
Publication date:
6.3.1986.
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