Original scientific paper

ChiraIity Determination of (19R)-, (19S)- and (19RS)-[19-3H,2H,1H]-3B-hydroxyandrost-5-en-17-one's

Eliahu Caspi ; Worcester Foundation for Experimental Biology Shrewsbury, MA 01545, USA
Chiu Chin Chang ; Worcester Foundation for Experimental Biology Shrewsbury, MA 01545, USA
Karl H. Busch ; Worcester Foundation for Experimental Biology Shrewsbury, MA 01545, USA
Thangavel Arunachalam ; Worcester Foundation for Experimental Biology Shrewsbury, MA 01545, USA

Abstract

The synthesized title compounds were converted to their. corresponding 4-en-3-one's which in turn were oxidized with selenium dioxide and hydrogen peroxide. The resulting seco acid lactones were oxidized by the Kuhn-Roth method to yield samples of acetic acid. The acetates were analyzed for chirality by the malate-synthetase fumarase procedure.

Keywords

Hrčak ID:

178035

URI

https://hrcak.srce.hr/178035

Publication date:

6.3.1986.

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