Professional paper
Recombinant factor Vlla therapy in a patient on long term anticoagulant treatment with a bleeding and acute subdural hematoma
Nataša Kovač
; Department of Anesthesiology, University Hospital Sestre milosrdnice, Zagreb, Croatia
Aleksandar Gopčević
; Department of Anesthesiology, University Hospital Sestre milosrdnice, Zagreb, Croatia
Josip Kovač
; Department of Anesthesiology, University Hospital Sestre milosrdnice, Zagreb, Croatia
Petar Gaćina
; Department of Anesthesiology, University Hospital Sestre milosrdnice, Zagreb, Croatia
Mladen Novkoski
; Department of Anesthesiology, University Hospital Sestre milosrdnice, Zagreb, Croatia
Abstract
In this paper we report on the successful correction of a coagulopathy with activated recombinant factor seven (rFVIIa) therapy which enabled surgical removal of a life threatening subdural hematoma. The severe coagulopathy developed due to long term warfarin therapy, which followed heart valvular reconstruction and replacement. The coagulopathy failed to improve following fresh frozen plasma and vitamin K therapy. Activated recombinant factor VII therapy became the treatment of choice, which enabled the life saving surgical removal of the subdural hematoma.
Keywords
activated recombinant factor seven; subdural hematoma; anticoagulant therapy; neurosurgery
Hrčak ID:
17028
URI
Publication date:
1.10.2007.
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