Short communication, Note
Preliminary investigations of prolonged occupational exposure to toxic substances on the level of some serum enzymes
J.Z. Hanke
; Institute of Occupational Medicine, Lodz
Abstract
The activity of four serum enzymes - aldolase, alkaline phosphatase, glutamic-oxalate transaminase, and glutamic-pyruvic transaminase - in two groups of workers chronically exposed to benzene and its homologues, as well as to lead has been investigated. Statistical analysis of the results obtained has shown that the contact with benzene and its homologues produces a drop in serum alkaline phosphatase activity and also, in some persons, a considerable drop in aldolase and glutamic-pyruvic transaminase serum level. The group of workers exposed to lead showed lower values of aldolase activity but higher SGOT/SGPT ratio than the control group. There was no evidence that these changes were caused by some other diseases, or malnutrition, or alcoholism. They seemed to be due only to a chronic exposure to benzene and lead.
Keywords
Hrčak ID:
180747
URI
Publication date:
25.3.1964.
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