Case report

Hepatitis D: report of two patients

Lejla Čalkić ; Kantonalna bolnica Zenica, Služba za zarazne bolesti, Zenica, BiH
Lejla Bajramović-Omeragić
Mensura Šeremet ; KCU Sarajevo, Klinička mikrobiologija, Sarajevo, BiH
Ibrahim Aličković ; Dom zdravlja Kakanj, Služba za higijensko-epidemiološku zdravstvenu zaštitu, Kakanj, BiH

Abstract

Hepatitis D virus (HDV) infection occurs only in HbsAg positive persons. About 350 million persons are infected with hepatitis B virus (HBV) worldwide and about 5% of them are infected with HDV. We present the first two reported cases of hepatitis D in Bosnia and Herzegovina. Patients were treated at the Department of Infectious Diseases, Cantonal Hospital Zenica during 2013 and 2014. Serological tests for HDV were performed at the Clinical Microbiology Department, Clinical Center Sarajevo. The first patient was a 67-year-old male with acute HBV-HDVcoinfection with severe, prolonged clinical course and favorable disease outcome: negative HBsAg, HDVAg and anti-HDV. The second patient was a 34-year-old male with chronic hepatitis B and HDV superinfection. It is necessary to raise awareness among health workers about the threats of combined HBV and HDV infection and provide better availability of HDV diagnostics.

Keywords

Hepatitis D; co-infection; superinfection

Hrčak ID:

182351

URI

https://hrcak.srce.hr/182351

Publication date:

31.3.2016.

Article data in other languages: croatian

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