Reumatizam, Vol. 62 No. suppl. 1, 2015.
Review article
THE CHALLENGE OF EARLY KNEE OSTEOARTHRITIS
Alberto Migliore
Emaunele Bizzi
Abstract
The identification of early stages of osteoarthritis, like the
pre-radiological stage characterized by few and mild symptoms,
would allow early preventive interventions, with the
aim of modifying the course of the disease. This could improve
the prognosis of patients affected by osteoarthritis
and lead to a significant reduction of the costs associated
with the management of this disease. To date, a clear clinical
definition of the early stages of osteoarthritis is still missing.
The OARSI initiative and the CHECK study are two
ongoing prospective studies among whose objectives is the
identification of early stages of osteoarthritis and the risk factors associated with its development. The Italian Society
for Rheumatology recently promoted an international
consensus for the definition of early knee osteoarthritis.
As a first step, a systematic literature review was performed
for the identification of possible definitions of early
osteoarthritis in scientific literature. As a second step, an
international panel of experts in the field of osteoarthritis
conceived, in several evaluation steps, a definition of early
symptomatic knee osteoarthritis.
Keywords
osteoarthritis; early; definition; knee
Hrčak ID:
182724
URI
Publication date:
10.10.2015.
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