Review article

FIBROMYALGIA: IS IT A RHEUMATIC DISEASE?

Dušanka Martinović Kaliterna
Ivona Božić

Abstract

Fibromylagia (FM) is a complex chronic condition usually presenting with symptoms of widespread
pain and fatigue, as well as sleep and cognitive disorders. Th e diagnosis is made by exclusion of other diseases and according
to the EULAR criteria. Th e treatment of the disease is multidisciplinary and associated with a better understanding of
the disease pathophysiology. Th e most commonly used drugs are tricylic antidepressants (TCA), serotonin and noradrenalin
uptake inhibitors (SNRI), anticonvulsants, and opioids. For the purpose of reducing the patient’s overall symptom
burden, adjunctive therapy with medicines targeted at specifi c symptoms, including sleep disorders, symptoms of
irritable bowel syndrome, or autoimmune diseases, should be considered. Current therapeutic models neither completely
treat FM symptoms nor benefi t all patients; therefore, further research on new therapeutic approaches is needed.

Keywords

Fibromyalgia – complications, diagnosis, physiopathology, psychology, therapy; Chronic pain – etiology, physiopathology; Fatigue – etiology; Sleep wake disorders – etiology; Cognition disorders – etiology; anticonvulsants – therapeutic use; Antidepressive agents – therapeutic use; Serotonin uptake inhibitors – therapeutic use

Hrčak ID:

182834

URI

https://hrcak.srce.hr/182834

Publication date:

19.10.2016.

Article data in other languages: croatian

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