Paediatria Croatica, Vol. 61 No. 1, 2017.
Review article
https://doi.org/10.13112/PC.2017.2
Chronic infl ammatory bowel diseases in children – novelties in the etiology, phenotype, diagnosis and treatment
Sanja Kolaček
; Klinika za dječje bolesti Zagreb
Iva Hojsak
Abstract
Chronic infl ammatory bowel diseases (IBD) including Crohn’s disease, ulcerative colitis and IBD unclassifi ed have been ever more
frequently diagnosed in childhood and adolescence. This tendency is highly important because the clinical picture, spread and
severity of these diseases greatly diff er when occurring in pediatric population. In particular, the younger the age at onset, the more
pronounced these characteristics are. The increase in the incidence of these diseases, as well as their diagnostic and therapeutic
specifi cities, has led to development of specifi c algorithms for IBD diagnosis and treatment in children. Numerous studies have been
conducted in an attempt to identify the cause of the growing prevalence of IBD, the etiopathogenetic mechanisms involved, and
what makes the clinical picture and therapeutic response diff erent in children. The aim of this review is to present and discuss the
specifi c features of IBD in children, with special reference to the epidemiology, phenotypic characteristics, and specifi cities of
diagnostic and therapeutic approach.
Keywords
Infl ammatory bowel diseases; Crohn disease; colitis, ulcerative; children
Hrčak ID:
184290
URI
Publication date:
28.3.2017.
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