Original scientific paper

SCHIZOPHRENIA AND BIPOLAR AFFECTIVE DISORDER: A DIMENSIONAL APPROACH

Demet Sağlam Aykut orcid.org/0000-0002-8432-3290 ; Karadeniz Technical University, Faculty of Medicine, Department of Psychiatry, Trabzon, Turkey
Filiz Civil Arslan ; Karadeniz Technical University, Faculty of Medicine, Department of Psychiatry, Trabzon, Turkey
Evrim Özkorumak ; Karadeniz Technical University, Faculty of Medicine, Department of Psychiatry, Trabzon, Turkey
Ahmet Tiryaki ; Karadeniz Technical University, Faculty of Medicine, Department of Psychiatry, Trabzon, Turkey

Abstract

Aim: Schizophrenia (SCH) and bipolar affective disorder (BAD) are currently classified separately according to the DSM (The
Diagnostic and Statistical Manual of Mental Disorders) and ICD (International Statistical Classification of Diseases and Related
Health Problems) standardized diagnostic guidelines. However, the validity of this categorical approach is controversial because
psychotic symptoms may be observed in both diagnoses. The purpose of this study was to compare the clinical and social
characteristics in a sample group consisting of patients diagnosed with SCH or BAD to help demonstrate the basic difficulty in the
current classification of SCH and BAD as two etiologically distinct diseases.
Subjects and methods: The study sample group consisted of 102 patients diagnosed with SCH and 92 patients diagnosed with
BAD. All of the participants were evaluated by Structured Clinical Interview for Diagnostic and Statistical Manual of Mental
Disorders, Fourth Edition with regard to beginning symptoms of the disease, the symptoms and signs of active disease period within
total disease duration, continuining residual symptoms in intermediate period. The patients were administered the Positive and
Negative Syndrome Scale, the Quality of Life Enjoyment and Satisfaction Questionnaire and the Social Functioning Scale.
Results: The SCH and BAD groups in this study were statistically similar in terms of sex, length of education, age at disease
onset, attempted suicide, quality of life and social functioning.
Conclusion: Our study findings indicated that the course of disease in patients with BAD-1, in which psychotic features
predominate and which exhibits a recurring course, shares various characteristics with SCH. It can be concluded that further
phenomenological and neurobiological evaluations are required for intermediate cases with similiar clinical characteristics with
schizophrenia and bipolar disorders.

Keywords

schizophrenia; bipolar affective disorder; dimensional approach

Hrčak ID:

184734

URI

https://hrcak.srce.hr/184734

Publication date:

28.6.2017.

Visits: 1.552 *