Croatica Chemica Acta, Vol. 90 No. 2, 2017.
Original scientific paper
https://doi.org/10.5562/cca3133
Graphene Based Composite Hydrogel for Biomedical Applications
Katarina Nešović
orcid.org/0000-0002-9022-6032
; University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia
Mohamed M. Abudabbus
; University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia
Kyong Yop Rhee
; Department of Mechanical Engineering, Kyung Hee University, 17104 Yongin, South Korea
Vesna Mišković-Stanković
orcid.org/0000-0001-6525-9820
; University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia
Abstract
In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV–vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene-based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Keywords
hydrogels; silver nanoparticles; poly(vinyl alcohol); graphene; nanocomposites; electrochemical synthesis
Hrčak ID:
185030
URI
Publication date:
3.7.2017.
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