Review article
Adverse Drug Reactions Associated with Statin Therapy
Luka Bielen
; Zavod za intenzivnu medicinu KBC Zagreb i Medicinski fakultet Sveučilišta u Zagrebu
Full text: croatian pdf 157 Kb
page 41-46
downloads: 540
cite
APA 6th Edition
Bielen, L. (2017). Adverse Drug Reactions Associated with Statin Therapy. Medicus, 26 (1 Farmakovigilancija), 41-41. Retrieved from https://hrcak.srce.hr/185269
MLA 8th Edition
Bielen, Luka. "Adverse Drug Reactions Associated with Statin Therapy." Medicus, vol. 26, no. 1 Farmakovigilancija, 2017, pp. 41-41. https://hrcak.srce.hr/185269. Accessed 2 May 2024.
Chicago 17th Edition
Bielen, Luka. "Adverse Drug Reactions Associated with Statin Therapy." Medicus 26, no. 1 Farmakovigilancija (2017): 41-41. https://hrcak.srce.hr/185269
Harvard
Bielen, L. (2017). 'Adverse Drug Reactions Associated with Statin Therapy', Medicus, 26(1 Farmakovigilancija), pp. 41-41. Available at: https://hrcak.srce.hr/185269 (Accessed 02 May 2024)
Vancouver
Bielen L. Adverse Drug Reactions Associated with Statin Therapy. Medicus [Internet]. 2017 [cited 2024 May 02];26(1 Farmakovigilancija):41-41. Available from: https://hrcak.srce.hr/185269
IEEE
L. Bielen, "Adverse Drug Reactions Associated with Statin Therapy", Medicus, vol.26, no. 1 Farmakovigilancija, pp. 41-41, 2017. [Online]. Available: https://hrcak.srce.hr/185269. [Accessed: 02 May 2024]
Full text: english pdf 157 Kb
page 41-41
downloads: 1.510
cite
APA 6th Edition
Bielen, L. (2017). Adverse Drug Reactions Associated with Statin Therapy. Medicus, 26 (1 Farmakovigilancija), 41-41. Retrieved from https://hrcak.srce.hr/185269
MLA 8th Edition
Bielen, Luka. "Adverse Drug Reactions Associated with Statin Therapy." Medicus, vol. 26, no. 1 Farmakovigilancija, 2017, pp. 41-41. https://hrcak.srce.hr/185269. Accessed 2 May 2024.
Chicago 17th Edition
Bielen, Luka. "Adverse Drug Reactions Associated with Statin Therapy." Medicus 26, no. 1 Farmakovigilancija (2017): 41-41. https://hrcak.srce.hr/185269
Harvard
Bielen, L. (2017). 'Adverse Drug Reactions Associated with Statin Therapy', Medicus, 26(1 Farmakovigilancija), pp. 41-41. Available at: https://hrcak.srce.hr/185269 (Accessed 02 May 2024)
Vancouver
Bielen L. Adverse Drug Reactions Associated with Statin Therapy. Medicus [Internet]. 2017 [cited 2024 May 02];26(1 Farmakovigilancija):41-41. Available from: https://hrcak.srce.hr/185269
IEEE
L. Bielen, "Adverse Drug Reactions Associated with Statin Therapy", Medicus, vol.26, no. 1 Farmakovigilancija, pp. 41-41, 2017. [Online]. Available: https://hrcak.srce.hr/185269. [Accessed: 02 May 2024]
Abstract
Statins are the most commonly used drugs for the treatment of hypercholesterolemia, with the aim of primary and secondary prevention of cardiovascular morbidity and mortality. Statins are considered safe drugs with lower incidence of adverse reactions than other hypolipemics. Skeletal muscle and liver related toxicities need to be mentioned as possible adverse reactions. In contrast to earlier recommendations, it is not considered necessary to conduct routine monitoring of transaminase levels during treatment with statins. New guidelines indicate that it does not lead to early recognition of clinically important liver toxicity due to statin treatment and is most often associated with drug interactions. Pharmacokinetic interactions of statins are important for the development of myopathy and rhabdomyolysis. Therefore, an individualized treatment approach is recommended considering the different metabolic pathways of various representatives of hypolipemic drugs.
Keywords
statins; adverse drug reactions; rhabdomyolysis; liver toxicity
Hrčak ID:
185269
URI
https://hrcak.srce.hr/185269
Publication date:
26.7.2017.
Article data in other languages:
croatian
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