Professional paper

https://doi.org/10.15836/ccar2017.311

Kidney Disease and Obesity.

Dubravka Mihaljević orcid.org/0000-0002-0051-4154 ; Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, University Hospital Centre Osijek, Osijek, Croatia

Abstract

Obesity is a global problem and a serious chronic disease. Some non-communicablediseases, includingobesity are among the leadingcauses of morbidity and mortality globally. Obesity is associated with a variety of disorders and diseases that have direct impact on kidney function. This primarily refers to diabetes mellitus, elevated arterial pressure, and metabolic syndrome. Obesity, even without associated diseases, favors development of chronic kidney disease (CKD). Obesity is associated with a number of kidney diseases such as glomerulopathies and nephrolithiasis, and influences kidney graft survival. Metabolic syndrome and diabetes mellitus type 2 are classic risk factors for CKD and cardiovascular disease development. Inflammation is one of the most important CKD and obesity characteristics, contributing to the development of glomerulosclerosis and tubulointerstitial atrophy. Along with glomerulopathy associated with obesity, focal segmental glomerulosclerosis with significant proteinuria is directly related to obesity. Adipose patients with IgA nephropathy have poorer disease prognosis.

Keywords

obesity; chronic kidney disease; glomerulopathy associated with obesity

Hrčak ID:

185344

URI

https://hrcak.srce.hr/185344

Publication date:

21.7.2017.

Article data in other languages: croatian

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