Professional paper

Four cases of metol poisoning

V. Palmović ; Zavod za sudsku medicinu i kriminalistiku, Medicinski fakultet, Zagreb
Jelena Frketić ; Zavod za sudsku medicinu i kriminalistiku, Medicinski fakultet, Zagreb

Abstract

After a brief account of the chemical properties of metol and its use, the author describes local lesions in occupational metol poisoning and the way in which they occur; after peroral application of metol a resorptive action beside the irritative effect on the mucous membranes of the gastrointestinal tract is noticeable; symptoms of experimental metol poisoning and lethal doses are discussed. The author reports four cases of accidental metol poisoning with fatal issue in one case. The post mortem findings and the results of toxicological analysis are given. The reducing effect of metol in tissues is also discussed. The author does not consider the formation of methemoglobin in blood very probable. After being resorbed, metal changes very quickly and no chemical evidence for its presence can be obtained. The transformation of methol in quinone derivates by oxydation is also partial. Minimal lethal dose for men by rectal application is estimated to 0.2 g/kg.

Keywords

Hrčak ID:

186450

URI

https://hrcak.srce.hr/186450

Publication date:

14.6.1955.

Article data in other languages: croatian

Visits: 1.126 *