Original scientific paper

Experimental infective pneumoconiosis

E.J. King ; postgraduate Medical School, University of London, London
C.V. Harrison ; postgraduate Medical School, University of London, London
G.P. Mohanty ; postgraduate Medical School, University of London, London
D.A. Mitchison ; postgraduate Medical School, University of London, London

Abstract

Quartz and coal-mine dusts were introduced into the lungs of rats by inhalation, in a high concentration, for four months, and then groups of these dusted animals were infected with a virulent strain of human tubercle bacillus (37 Rv). Dusting was continued for a further period of ten months in the case of coal-mine dust. No variation in lung pathology was seen in the quartz groups, although both produced classical silicotic nodules. In the coal-mine dust the infective group showed slightly more fibrosis, diffuse in nature, than either the noninfected or the tuberculous control group. These are preliminary experiments, and the results must be considered as both tentative and not very conclusive. Work is being continued.

Keywords

Hrčak ID:

187051

URI

https://hrcak.srce.hr/187051

Publication date:

15.9.1953.

Article data in other languages: croatian

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