Review article

Aquagenic urticaria: A perplexing physical phenomenon

Cindy Wassef ; Stony Brook Medicine
Anacristina Laureano
Robert A. Schwartz

Abstract

Aquagenic urticaria (AQ) is a rare physical urticaria induced by contact with water. It may be distinctive clinically, evident as 1-2 mm folliculopapular urticaria, a pattern also characteristic of cholinergic urticaria. AQ has a truncal and upper extremity distribution within 20-30 minutes after contact with water, regardless of its temperature or source. AQ is usually symptomatic with mild to severe pruritus and a burning sensation. The mechanism by which water produces mast cell degranulation and histamine release remains unclear. We review its clinical presentation, diagnostic parameters, differential diagnosis, and treatment.

Keywords

Hrčak ID:

187820

URI

https://hrcak.srce.hr/187820

Publication date:

19.10.2017.

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