Review article

PSORIASIS

Marija Kaštelan

Abstract

Psoriasis is a chronic infl ammatory skin disease aff ecting about 2-3% of the world population, and around 1.6%
of the population in Croatia. Nowadays, psoriasis is considered to be a multisystemic infl ammatory disease with a
variety of comorbidities such as hypertension, diabetes, cardiovascular diseases, infl ammatory bowel and eye diseases,
and psychosocial comorbidities. Th e most common comorbidity in psoriasis is psoriatic arthritis, aff ecting about
30-40% of patients, although accurate epidemiological data are not available. Nowadays, the new paradigm of psoriasis
and psoriatic arthritis uses the term psoriatic disease with skin and/or musculoskeletal manifestations. Contemporary
treatment of psoriasis relies on evidence-based medicine including clinical experience, scientifi c evidence, but also
patients’ desires when choosing the appropriate therapy. Biological therapy in the treatment of psoriasis represents a
signifi cant progress compared to classical psoriasis therapy, due to the high effi cacy and safety of new drugs.

Keywords

Psoriasis – diagnosis, genetics, immunology, therapy; Comorbidity; Arthritis, psoriatic; Biological therapy

Hrčak ID:

188334

URI

https://hrcak.srce.hr/188334

Publication date:

25.10.2017.

Article data in other languages: croatian

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