Review article

Cancer of the ovary, fallopian tube and peritoneum: surgical management

Damir Danolić ; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ilija Alvir ; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ivica Mamić ; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Lucija Kostić ; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Darko Tomica ; Department of Gynecology and Obstetrics, General Hospital Scheibbs, Scheibbs, Austria
Marko Puljiz ; School of Medicine Split, University of Split, Croatia
Mario Puljiz ; Department of Gynecologic Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia

Abstract

Surgery is the cornerstone of eff ective management of the ovarian, tubal and peritoneal cancer. In 2014 the International Federation of Gynecology and Obstetrics (FIGO) published a new classifi cation collectively covering cancer of ovary, fallopian tube and peritoneum as well as malignant ovarian germ cell tumors and malignant sex-cord stromal tumors. Comprehensive surgical staging according to the 2014 FIGO classifi cation system plays an important role in management of
apparently early stage of ovarian, tubal and peritoneal cancer. Primary debulking (cytoreductive) surgery followed by paclitaxel and platinum based combination chemotherapy is the cornerstone of the advanced-stage disease treatment. In cases of suboptimal primary cytoreduction, interval debulking surgery performed after two to four cycles of chemotherapy based on the clinical judgment of the gynecologic oncologist is second att empt to achieve optimal cytoreduction. Secondary cytoreductive surgery can be considered in patients with platinum-sensitive locally recurrent ovarian cancer. The volume of
residual tumor remaining after these surgical approaches is one of the most important independent prognostic factors for survival.

Keywords

cancer of the ovary; fallopian tube and peritoneum; surgical staging; debulking surgery; residual tumor

Hrčak ID:

189804

URI

https://hrcak.srce.hr/189804

Publication date:

10.12.2015.

Article data in other languages: croatian

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