Original scientific paper

https://doi.org/10.17559/TV-20160723152540

Three-dimensional biomechanical model of benign paroxysmal positional vertigo in the semi-circular canal

Nebojsa Zdravkovic orcid.org/0000-0003-0877-3684 ; Faculty of Medical Science, University of Kragujevac, Svetozara Markovica 69, 34000 Kragujevac, Serbia
Zarko Milosevic ; Faculty of Engineering, University of Kragujevac, Sestre Janjica 6, 34000 Kragujevac, Serbia / BioIRC Research and Development Center for Bioengineering, Prvoslava Stojanovica 6, 34000 Kragujevac, Serbia
Igor Saveljic orcid.org/0000-0002-0707-5174 ; Faculty of Engineering, University of Kragujevac, Sestre Janjica 6, 34000 Kragujevac, Serbia / BioIRC Research and Development Center for Bioengineering, Prvoslava Stojanovica 6, 34000 Kragujevac, Serbia
Dalibor Nikolic orcid.org/0000-0001-5491-4586 ; Faculty of Engineering, University of Kragujevac, Sestre Janjica 6, 34000 Kragujevac, Serbia / BioIRC Research and Development Center for Bioengineering, Prvoslava Stojanovica 6, 34000 Kragujevac, Serbia
Vladimir Miloradovic ; Faculty of Medical Science, University of Kragujevac, Svetozara Markovica 69, 34000 Kragujevac, Serbia
Nenad Filipovic orcid.org/0000-0001-9964-5615 ; Faculty of Engineering, University of Kragujevac, Sestre Janjica 6, 34000 Kragujevac, Serbia / BioIRC Research and Development Center for Bioengineering, Prvoslava Stojanovica 6, 34000 Kragujevac, Serbia

Abstract

Benign Paroxysmal Positional Vertigo (BPPV) is one of the most common vestibular disorders occuring due to the presence of basophilic particles in the semicircular canals (SCC). Three-dimensional biomechanical model of the SCC is described with full 3D fluid-structure interaction of particles, wall, cupula deformation and endolymph fluid flow. The model of the SCC with parametric defined dimension and fully 3D three SCC from patient specific 3D reconstruction is presented. Navier-Stokes equations with continuity equations described fluid flow while Arbitrary-Lagrangian Eulerian (ALE) formulation is used for mesh motion. Fluid-structure interaction for fluid coupling with cupula deformation is used. Particle tracking algorithm has been used for particle motion. Different size and number of particles with their full interaction between themselves, wall and cupula deformation are used. Velocity distribution, shear stress and force from endolymph side are presented for parametric one SCC and patient specific three SCC. All the models are used for correlation with the same experimental protocols with head moving and nystagmus eye tracking. Full fluid-structure interaction of otoconia particles, wall, cupula deflection and endolymph flow in three-dimension give more details and understanding of the pathology of the specific patient in standard clinical diagnostic and therapy procedure for BPPV.

Keywords

biomechanical model; BPPV; fluid-structure interaction; semi-circular canals; sedimenting particle

Hrčak ID:

190173

URI

https://hrcak.srce.hr/190173

Publication date:

3.12.2017.

Article data in other languages: croatian

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