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Pain After Tooth Extraction Masking Primary Extranodal Non-Hodgkin’s Lymphoma of the Oral Cavity

Dragana Gabrić Pandurić
Tihomir Kuna
Davor Katanec

Full text: croatian pdf 353 Kb

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Full text: english pdf 353 Kb

page 366-374

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Malignant lymphoma of the oral region are uncommon and account for approximately 3.5% of all oral malignancies. In this report, a case of primary non-Hodgkin lymphoma of the left mandible is presented. The spontaneous and intermittent pain of the left mandible had continued after third left molar extraction. Intraoral examination
revealed healing retardation of the postextraction socket. A panoramic radiograph revealed a radiolucency in the posterior mandibular region with irregular margins. After the 10-day course of antibiotics the spontaneous pain diminished, but the inadequacy of the healing at the extraction site was still present. We initially
misdiagnosed it as chronic osteomyelitis. Based on the histological and immunohistochemical examination, we made the diagnosis of diffused large cell lymphoma of the B-cell type. After the combination of chemotherapy and radiotherapy patient showed complete remission with the disappearance of all clinical evidence of disease.
The diagnosis of extranodal lymphoma of the jaw may be chalenging, because frequently there is a low index of clinical suspicion and malignant tumor may mimic common oral and dental pathological conditions. Dentists can play the important rule in the early detection of the malignant lymphoma of the oral cavity.


Mouth Neoplasms, Lymphoma, Non-Hodgkin

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