Croatica Chemica Acta, Vol. 55 No. 4, 1982.
Original scientific paper
Geometrical Isomers in the 2-Amino-(2-Hydroxy-)cyclohexane- 1,3-, -1,4-, -1,5-, and -1,6-dicarboxylic Acids Series
V. Škarić
; Laboratory of Stereochemistry and Natural Products, »Rudjer Boskovic« Institute, 41001 Zagreb, Croatia, Yugoslavia
V. Turjak-Zebić
; Laboratory of Stereochemistry and Natural Products, »Rudjer Boskovic« Institute, 41001 Zagreb, Croatia, Yugoslavia
Abstract
The synthesis of previously inaccessible cis-cis-(a) trans-
cis-(b), and trans-trans-(c) stereoisomers in the diethyl 2-hydroxy-(
IV) and 2-amino-(VIl)-cyclohexane-1,3-dicarboxylates ser;ies
is described. The geometries of these isomers and their 0- (VI)
and N- (X) benzoyl derivatives are established by NMR spectroscopy
in relation to deshielding effects on the geminal C-2 protons.
Keywords
Hrčak ID:
194260
URI
Publication date:
15.12.1982.
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