Croatica Chemica Acta, Vol. 54 No. 2, 1981.
Original scientific paper
Synthesis of New Formyl Halo N-methylimidazole Derivatives
M. El Borai
; Department of Chemistry, Faculty of Science, University of Tanta and University of Ain Shams, Egypt
A. H. Moustafa
; Department of Chemistry, Faculty of Science, University of Tanta and University of Ain Shams, Egypt
M. Anwar
; Department of Chemistry, Faculty of Science, University of Tanta and University of Ain Shams, Egypt
A. G. Ghattas
; Department of Chemistry, Faculty of Science, University of Tanta and University of Ain Shams, Egypt
Abstract
Bromo-formyl imidazoles 16-20 have been prepared by three
different ways. The first consisted of conversion of bromo or iodo
imidazoles 1-6 into diethyl acetals 13-15, and subsequent hydrolysis
into formyl derivatives 7-9. In the second, bromination of.
formyl imidazoles with NBS afforded compounds 16-18 in 45-70°/o
yield. The third method used direct formylation of bromo imidazoles
10-12 with n-BuLi/DMF reagent into compounds 16, 19, and 20.
Keywords
Hrčak ID:
194338
URI
Publication date:
20.7.1981.
Visits: 1.063 *