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Original scientific paper

Chemistry of 1,3-Dioxepins. I. Reaction of 4, 7-Dihydro- 1,3-dioxepins with Nitryl Chloride

M. Dumić ; PLIVA, Pharmaceutical and Chemical Works, 41000 Zagreb
M . V. Proštenik ; PLIVA, Pharmaceutical and Chemical Works, 41000 Zagreb
I. Butula ; PLIVA, Pharmaceutical and Chemical Works, 41000 Zagreb


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Abstract

The reaction of 4,7-dihydro-1,3-dioxepins II with nitryl chloride
in chloroform of light petroleum as a solvent gave a mixture of
5-chloro-6-nitro-dioxepans III and 5,6-dichloro-dioxepans IV. In
alkylnitriles as solvents, the corresponding 6-acylamino-5-chloro-
dioxepans VII were also formed. Hydrodechlorination of III in the
presence of triethylamine afforded 5-nitro-4,7-dihydro-1,3-dioxep-
~ L

Keywords

Hrčak ID:

195950

URI

https://hrcak.srce.hr/195950

Publication date:

22.12.1978.

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