Original scientific paper

Cyclization of Diethyl(phthalimidoacetyl)malonate into 3-(Phthalimidomethyl)pyrazolin-5-ones

N. Bregant ; Laboratory of Organic Chemistry and Biochemistry, Faculty of Science, and Department of Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb, 41000 Zagreb, Croatia, Yugoslavia
I. Perina ; Laboratory of Organic Chemistry and Biochemistry, Faculty of Science, and Department of Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb, 41000 Zagreb, Croatia, Yugoslavia
M. Malnar ; Laboratory of Organic Chemistry and Biochemistry, Faculty of Science, and Department of Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb, 41000 Zagreb, Croatia, Yugoslavia

Abstract

The cyclic parent (II) of the title series, and the following
1- or/and 4-substituted derivatives therefrom: 4-ethoxycarbonyl
(III), 1-phenyl-4-ethoxycarbonyl (IV), and 1-phenyl (V), were prepared
by conventional methods. (III) and (IV) gave each a single
product on methylation with ethereal diazomethane. Structures of
these products, and those of (II) - (V), are discussed on the basis
of proton magnetic resonance and infrared spectra.

Keywords

Hrčak ID:

196155

URI

https://hrcak.srce.hr/196155

Publication date:

26.4.1978.

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