Original scientific paper

Synthesis of Amino Acids by Cathodic Cleavage of Phenylhydrazones of a-Keto Acids

I. Tabaković ; Faculty of 'Technology, University of Banjaluka, 78000 Banjaluka, Bosnia and Hercegovina, Yugoslavia
M. Trkovnik ; Faculty of 'Technology, University of Banjaluka, 78000 Banjaluka, Bosnia and Hercegovina, Yugoslavia
M. Džepina ; Faculty of 'Technology, University of Banjaluka, 78000 Banjaluka, Bosnia and Hercegovina, Yugoslavia

Abstract

Electrochemical synthesis of amino acids by reduction of
phenylhydrazones of the folowing a-ketoacids: pyruvic, a-ketovaleric,
a-ketoglutaric and a-ketooctane acid was studied. The
corresponding a-amino acids were obtained in 44--55~/o yield using
controlled potential electrolysis on mercury pool electrode in 0.5 M
HCl aqueous ethanol solution.
A mechanism rationalizing the reduction products of the phenylhydrazone
of pyruvic acid as well as polarographic and coulometric
data are proposed.

Keywords

Hrčak ID:

196346

URI

https://hrcak.srce.hr/196346

Publication date:

20.7.1977.

Visits: 428 *