Conference paper

Kinetics and Mechanisms of Oxidation of Hemoprotein Model Compounds

C. K. Chang ; Department of Chemistry, University of California, San Diego, La Jolla, California 92093, USA
D. Powell ; Department of Chemistry, University of California, San Diego, La Jolla, California 92093, USA
T. G. Traylor ; Department of Chemistry, University of California, San Diego, La Jolla, California 92093, USA

Abstract

The kinetics of reaction of oxyheme complexes with dithionite
ion and with deoxyheme were studied. Because rates of autooxidation
of oxyheme complexes were inversly proportional to oxygen
pressure and proportional to the square of the total heme concentration,
it was concluded that the reaction proceeds through Heme-
00-Heme as suggested by Cohen and Caughey. The direct reaction
of dithionite ion with oxyheme complexes accords with the Fe+o 2- ·
formulation of the iron-oxygen bond.

Keywords

Hrčak ID:

196369

URI

https://hrcak.srce.hr/196369

Publication date:

30.3.1977.

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