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Croatica Chemica Acta, Vol. 48 No. 3, 1976.

Short communication, Note

The in vivo Effect of Ultraviolet Irradiation (290-350 nm) on Epidermal Chromatin

A . Kornhauser ; Harvard Scholl of Dental Medicine Boston, Massachusetts 02115
M. A. Pathak ; Department of Dermatology Harvard Medical School Boston, Massachusetts 02115
E. Zimmermann ; University of Munster Physiological Institute 44 Munster, Germany
G. Szabo ; Harvard Scholl of Dental Medicine Boston, Massachusetts 02115

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Abstract

In vivo ultraviolet radiation (290-350 nm, 800 J/m2
) in the absence of any exogenously added sensitizer induced oross-ltnkirng of DNA to protein in chromatin isolated from guinea pig epidermis.
The chemical properties and the biologic activity of epidermal
chromatin isolated from both irradiated and non-irradiated
specimens were examined. One hour post-irradiation the lesion was
no more detectable, indicating that a repair process was effective
1n the viable mammalian epidermis.

Keywords

Hrčak ID:

196470

URI

https://hrcak.srce.hr/196470

Publication date:

23.9.1976.

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