Case report

Amyloidosis in chronic juvenile arthritis in adults

Ivan Zgradić

Abstract

An attempt has been made to present clinical picture of a very rare case of secondary amyloidosis as a complication of chronic juvenile arthritis in adults. Secondary amyloidosis is one of the most severe complications of chronic juvenile arthritis in adults and the most frequent cause of death. Its occurrence varies from below 1 % in the USA and Australia to 18 % in Poland, while in most European countries it ranges between 7 % and 8 %. On the average, this disease occurs 8—10 years after the onset of arthritis. The first clinical symptoms are abdominal pains, sometimes with diarrhea, pasty edema of the lower leg, hypertension as well as enlarged liver and spleen. Two clinical cases of secondary amyloidosis are presented. One died of renal failure 4.5 years after the onset of nephrotic syndrome, whereas the other one died of acute secondary amyloidosis occurring 5 years after the onset of the disease which had been unsatisfactorily controlled with gold and low doses of
prednisone and dichlophenac.

Keywords

amyloidosis arthritis; juvenile rheumatoid

Hrčak ID:

196967

URI

https://hrcak.srce.hr/196967

Publication date:

1.12.1989.

Article data in other languages: croatian

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