Medicinski vjesnik, Vol. 20 No. (1), 1988.
Original scientific paper
Beta-2 microglobulinemia - glomerular filtration rate
Katarina Kruhonja
Danka Gall
Jasna Grdić
Zrinka Dokonal
Željko Klir
Aleksandar Rusić
Abstract
The correlation of serum beta-2-microglobulin was examined and serum creatinine with glomerular filtration rate (GF). GF was evaluated by clearence Cr5, -EDTA. The best description of correlation between serum beta-2-microglobulin (also and serum creatinin) and GF was by inversely potential function. The coefficient of correlation for the beta-2-microglobulin was —0.9427 and for the creatinin test —0.9114. The difference between obtained coefficients of correlations was statistically significant (p = 0.001 t = 2.68). More important is the significant difference between the obtained coefficients of regression. In the logaritmic scale the coefficient of regression of the straight line which described the relation of serum level of beta-2-microglobulin and GF was —0.9512 and —0.7979 for the relation of the serum level of creatinine and GF. It indicates that beta-2-microglobulin is more similar to the ideal endogenic substance for evaluation of GF and shows better sensitivity for the detection of moderately reduced GF.
Keywords
beta-2-microglobulinemia; glomerular filtration
Hrčak ID:
197071
URI
Publication date:
1.12.1988.
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