Preliminary communication

Lipoproteins in serum in non-insulin dependent diabetes mellitus after treatment with insulin

Ante Ivandić
Ivana Prpić
Darko Šulava
Dubravka Švarc
Marija Kuveždić
Dubravka Grbeša

Abstract

HbA1, HDL-cholesterol, total cholesterol and tri- glyceride concentrations were measured in 18 patients vith non-insulin dependent diabetes mellitus previoisly treated with glibenclamide, before and three nonths after the combined treatment with insulin and glibenclamide. HbA, concentration fell significantly after three months (p < 0.01), HDL-cholesterol did not change (1.27 + 0.47 mmol/L to 1.26 + 0.46 mmol/L, p > 0.05), whereas LDL-cholesterol fell slightly but insignificantly (4.32 + 0.87 mmol/L to 4.01 + 0.99 mmol/L, p > 0.05). There was a significant reduction in total cholesterol (p < 0.05) and triglyceride concentrations (p < 0.01), probably reflecting the fall in VLDL-cholesterol concentration. No significant connection has been observed between HbAj and HDL-cholesterol concentrations.

Keywords

insulin; lipoproteins; serum; diabetes

Hrčak ID:

197203

URI

https://hrcak.srce.hr/197203

Publication date:

1.12.1988.

Article data in other languages: croatian

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