Short communication, Note

Electrochemical Reduction of Intermediates in the Vitamin B6 Production. II. Reduction of 2-Methoxymethyl-3-nitro-4-methyl- 5-cyano-6-chloropyridine

M. Laćan ; Faculty of Technology, University of Zagreb
I. Tabaković ; Faculty of Technology, University of Zagreb
J. Hranilović ; Faculty of Technology, University of Zagreb
Z. Vajtner ; Faculty of Technology, University of Zagreb
R. Hranilović ; Faculty of Technology, University of Zagreb

Abstract

2-Methoxymethyl-3-nitro-4-methyl-5-cyano-6-chloropyridine
(I) was reduced on a mercury-pool in an electrolytic cell with a
diaphragm. A mixture of acetic and hydrochloric acid was used
as catholyte and diluted hydrochloric acid as anolyte. Compound
I was reduced at - 0.5 V to 2-methoxymethyl-3-amino-4-methyl-
5-cyano-6-chloropyridine (II) (yield 67-820/o). Compound II was
reduced at - 0.9 V to 2-methoxymethyl-3-amino-4-methyl-5-
cyanopyridine (Ill) (yield 54-83-0/o). Compound III was reduced
at -1.1 V to 2,4-dimethyl-3-amino-5-cyanopyridine (IV) (yield
48-660/o Compound IV was reduced at constant current density
to 2,4-dimethyl-3-amino-5-aminomethylpyridine (V) (yield 82,40/o).
Polarographic waves of I, II, and III are defined and character of
limiting currents was determined according to the usual criteria.

Keywords

Hrčak ID:

197214

URI

https://hrcak.srce.hr/197214

Publication date:

10.11.1972.

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