Review article

Laryngopharyngeal reflux is not gastroesophageal reflux

Andrijana Včeva
Hrvoje Mihalj
Željko Zubčić
Željko Kotromanović
Darija Birtić
Martina Mihalj
Mirjana Grebenar
Vladimir Bajtl

Abstract

Laryngopharyngeal refux and gastroesophageal reflux are two different clinical entities, two different diseases which differ in symptoms, clinical manifestations, mechanism of reflux, diagnostic criteria and therapeutic schedules. Main symptoms of LPR are hoarseness, clearing of throat, postnasal drip, swallowing difficulties, coughing, breathing difficulties and in only 6 to 11 % of patients heartburn, chest pain, indigestion or stomach acid coming up. Main clinical signs of LPR are: pseudosulcus vocalis, ventricular obliteration, erythema/hyperemia, vocal fold edema, diffuse laryngeal edema, posterior commissure hypertrophy, granuloma/granulations and thin endolaryngeal mucus. The diagnosis is usually based on a combination of diagnostic signs and symptoms, 24-hour pH-metry, multichannel intraluminal impedance and pepsin in saliva. In therapy proton pump inhibitors are being applied twice a day.

Keywords

Laryngopharyngeal reflux; Gastroesophageal reflux; Pepsin; 24-hour pH-metry; Proton pump inhibitors

Hrčak ID:

198038

URI

https://hrcak.srce.hr/198038

Publication date:

1.12.2011.

Article data in other languages: croatian

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