Review article
The Metabolic Syndrome - Historical Notice
Velimir Božikov
Abstract
In 1988, G. Reaven described the role of
insulin resistance and hyperinsulinism and gave it the name
by which it has become widely recognised, "Syndrome X".
A contemporary defi nition of Metabolic Syndrome refers to a
cluster of metabolic disorders related to insulin resistance,
a state that is often associated with a high-risk overweight/
obesity phenotype. Today, metabolic syndrome is the most
important source of new diabetic cases, as well as the
major cause of coronary heart disease.
Keywords
insulin resistance; syndrome X; metabolic syndrome; type 2 diabetes; coronary heart disease
Hrčak ID:
18990
URI
Publication date:
15.11.2004.
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