Review article

Metabolic Insulin Resistance and Purine Metabolism

Vanja Zjačić-Rotkvić
Darko Katalinić
Maja Berković

Abstract

Metabolic syndrome or syndrome X is a
complex association of several interrelated abnormalities
that increase the risk of cardiovascular and cerebrovascular
diseases. These diseases include diabetes, hypertension,
dyslipidaemia, hyperuricemia, obesity and other diseases
resulting from insulin resistance. From a clinical standpoint,
hyperuricemia should alert a clinician to an overall increased
risk of vascular diseases. The topical role of uric acid and its
relation to cardiovascular and cerebrovascular diseases and
insulin resistance, renal disease and hypertension is rapidly
evolving and it is one of essential factors in the clinical
clustering phenomenon of the metabolic syndrome and type
2 diabetes mellitus.

Keywords

insulin resistance; metabolic syndrome; hyperuricemia; diabetes type 2; cardiovascular and cerebrovascular diseases

Hrčak ID:

19009

URI

https://hrcak.srce.hr/19009

Publication date:

15.11.2004.

Article data in other languages: croatian

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