Acta clinica Croatica, Vol. 57. No. 1., 2018.
Original scientific paper
https://doi.org/10.20471/acc.2018.57.01.13
Globus Pharyngeus: A Symptom of Increased Thyroid or Laryngopharyngeal Reflux?
Sani Penović
orcid.org/0000-0001-5984-4425
; University Department of Surgery, Split University Hospital Centre, Split, Croatia
Željka Roje
; Private Practice of Otorhinolaryngology, Split, Croatia
Dubravka Brdar
; Department of Nuclear Medicine, Split University Hospital Centre, Split, Croatia
Sanda Gračan
; Department of Nuclear Medicine, Split University Hospital Centre, Split, Croatia
Ana Bubić
; Institute of Emergency Medicine of Split-Dalmatia County, Split, Croatia
Jadranka Vela
; University Department of ENT, Head and Neck Surgery, Split University Hospital Centre, Split, Croatia
Ante Punda
; Department of Nuclear Medicine, Split University Hospital Centre, Split, Croatia
Abstract
The aim of this study was to investigate the relationship between globus pharyngeus and laryngopha-ryngeal reflux, as well as between globus and thyroid volume. A two-year prospective study included 56 patients aged 18-75 with globus symptom. Anthropometric, clinical and laboratory data were collected. All patients filled-out the Glasgow Edinburgh Throat Scale (GETS) and then underwent thyroid ultrasound. Morphological changes of the larynx were detected by direct laryngoscopy and classified by the Reflux Finding Score (RFS). If RFS >7, the diagnosis of laryngopharyngeal reflux was made and therapy with proton pump inhibitors initiated. According to GETS, there was significant difference between patients with normal volume and those with large thyroid volume. There was no statistically significant difference between patients with RFS <7 and RFS >7. In conclusion, the incidence and severity of globus pharyngeus do not definitely indicate laryngopharyngeal reflux. It is more common in patients with normal thyroid volume.
Keywords
Laryngopharyngeal reflux; Pharyngeal diseases; Thyroid gland; Ultrasonography; Proton pump inhibitors; Surveys and questionnaires
Hrčak ID:
202058
URI
Publication date:
1.3.2018.
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