Medicus, Vol. 9 No. 1_Kronične bolesti, 2000.
Review article
Azithromycin in the Treatment of Ch. Trachomatis Asymptomatic Urogenital Infections
Višnja Škerk
Zvonimir Strapač
Slavko Schönwald
Bruno Baršić
Adriana Vince
Vladimira Kružić
Nataša Šterk-Kuzmanović
Abstract
The detection and treatment of persons with
asymptomatic Chlamydia trachomatis (CT) infection is important
in preventing the infection spread and the development
of its complications. Objectives: To find the most effective
antimicrobial therapy for the treatment of asymptomatic urogenital
infection caused by Chlamydia trachomatis. The patients
were randomized into 4 groups regarding antimicrobial
therapy: 1) azithromycin 1x1.0 g in a single dose, 2) azithromycin
1x0.5 g for 6 days, 3) doxycycline 2x100 mg for 7
days, 4) doxycycline 2x100 mg for 14 days. Bacteriological
efficacy was evaluated 3-4 weeks after the end of the treatment.
There was no significant difference between the groups.
Conclusion: Since no consensus has been reached on
the treatment of asymptomatic CT urogenital infections and
different therapy regimens, we recommend that the therapy
efficacy be evaluated in every single case by one of the standardized
microbiological methods.
Keywords
Chlamydia trachomatis; asymptomatic infection; treatment
Hrčak ID:
19193
URI
Publication date:
26.1.2000.
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