Professional paper

Difference in anaemia expression in men and women with renal failure treated with peritonial dyalisis

Kristina Marović Frketić orcid.org/0009-0008-1422-9283 ; Opća bolnica Zadar, Odjel za interne bolesti
Dario Nakić ; Opća bolnica Zadar, Odjel za interne bolesti

Abstract

Anemia is recognized as a common complication of chronic kidney disease (CKD) with a significant impact on morbidity and mortality and a decline in quality of life and health care costs. Guidelines for the treatment of CKD anemia do not specify sex-specific Hb targets. There are similarities among genders in the basic physiology of anemic CKD, but there is growing evidence with respect to differential responses to anemia between genders.
We performed a retrospective analysis of patients during the first six months of peritoneal dialysis (PD) treatment. Gender differences in Hb level seen in the healthy populations are maintained in subjects with end stage renal disease at PD inception and after six months of treatment. A greater proportion (15-30%) of females require erythropoiesis stimulating agents (ESA) than males. The average monthly EPO dose was 70% higher in females. Despite lower absolute levels of Hb, women manifest higher Hb levels relative to gender-specific normative values than men.

Keywords

anemia; chronic renal insufficiency

Hrčak ID:

204701

URI

https://hrcak.srce.hr/204701

Publication date:

20.8.2018.

Article data in other languages: croatian

Visits: 1.710 *